MALDI PharmaPulse is a complete accumulation spectrometry based screening band-aid advised to advance all phases of biologic discovery. The arrangement offers the advantage of authentic label-free apprehension of built-in substrates and articles in anatomic biochemical assays. An ultrafast MALDI-TOF arrangement delivers analytic after-effects in beneath than 1 additional per sample authoritative it abnormally ill-fitted for Aerial Throughput Screening (HTS) applications.
This avant-garde band-aid delivers cogent cost-per-sample reductions due to the acutely low bread-and-er and reagent usage, bargain decay bearing including chancy solvents acute difficult disposal, and the aishment of any sample pre-treatment accomplish such as SPE or HPLC. Appraisal development with the MALDI PharmaPulse is simple and accelerated while sample and abstracts processing is absolutely automated. Combined with the able-bodied apparatus performance, these factors decidedly access lab efficiency.
Fully Automatic Bowl Management, Alertness and Loading
Based on Bruker’s bazaar arch FLEX alternation cast assisted laser desorption ionization time of flight accumulation spectrometers (MALDI-TOF), the MALDI PharmaPulse provides authentic MS based 96, 384 and 1536 bowl account capabilities. The appraisal of a complete 1536 ambition bowl takes beneath than 25 minutes. Subsequent ambition plates are automatically exchanged with the included automation amalgamation or with custom solutions.
All of Bruker’s MALDI-TOF systems absorb patented smartbeam™ laser technology for unrivalled speed, sensitivity, and resolution.
Bruker’s flagship FLEX alternation – quick and reliable after-effects from the aboriginal sample amounts.
MALDI PharmaPulse allowances includes:
Automated abstracts accretion and processing
Comprehensive and easy-to-use, Bruker’s Compass™ software amalgamation provides absolutely automatic abstracts accretion and processing capabilities. Flexible abstracts achievement formatting allows accessible alteration to added software systems for added abstracts processing or visualization.
Shorter time to after-effects and lower costs
Significant reductions in bread-and-er and reagent acceptance and decay bearing aftereffect in abundant lower cost-per-sample.
Plate Account with MALDI-TOF MS
The MALDI PharmaPulse appearance a abounding automation amalgamation from HighRes Biosolutions that seamlessly prepares and endless MALDI plates into the FLEX alternation MALDI-TOF system. Major apparatus of the pre-configured arrangement include:
HighRes Biosolutions Cellario activating scheduling software seamlessly controls the automation and MALDI-TOF apparatus of the complete solution. Cellario integrates all the accessories to accommodate a single, adamant front-end alternation point for the end user. Through agreement design, adjustment creation, pre-run appraisal and run-time control, Cellario is accurately advised to optimize the throughput, sample alertness and ability appliance of the MALDI PharmaPulse.
TTP Labtech’s nanoliter aqueous handler, mosquito, enables the aerial throughput alertness of the MALDI sample plates. mosquito’s altered absolute displacement technology allows sample and cast to be sequentially aspirated and accompanying dispensed to aftermath uniform, constant spots in the sub microliter range.
Highly authentic pipetting and accession allows spots to be set up in aerial body 1,536 arrays to accredit fast and able analysis. The constant attributes of the spots agency that abounding laser shots can be accursed at the aforementioned area after compromising abstracts affection and is key to the all-embracing throughput of the system.
The disposable pipette tips acclimated by mosquito can be done and re-used to abbreviate active costs and ensure arrangement reliability. Absolute displacement technology additionally offers best reproducibility alike back ambidextrous with the altered aqueous classes acclimated for sample and matrix. The adamant attributes of the tips additionally acquiesce them to bore foil-sealed antecedent plates, which is capital for canning of the airy cast and ablution solutions.
The mosquito apparatus is able of advancing a 1,536 MALDI bowl in beneath than 1 additional per able-bodied – befitting clip with the appraisal of the MALDI-TOF and advancement all-embracing throughput.
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